Mohs Surgery with the VivaCell 2500

The VivaCell® 2500 is a laser confocal microscope that images thick, excised tissue with cellular resolution during the Mohs Surgery procedure. Thick tissue specimens are loaded into a compact tissue cassette with no freezing, sectioning, or staining; cellular resolution images are obtained as soon as a cassette is placed on the VivaCell stage. The specimen can then be manually or automatically scanned, using the convenient mapping routines of the VivaCell's application software.

Lucid introduced its first ex vivo confocal imager, the VivaScope® 2000, in 1997. From these efforts, Lucid gained valuable experience working with medical professionals at clinical research centers and hospitals around the world. This experience led to the development of the improved VivaCell® 2500 ex vivo microscope for imaging thick surgical tissue specimens, such as those encountered in the Mohs surgery procedure.

The VivaCell® 2500 offers high resolution and simple handling of thick tissue specimens in a small, user-friendly size. The VivaCell® 2500 also provides improved ergonomics — and a lower cost than was possible with previous instruments. No other imager combines such an extensive feature set in an easy-to-use, affordable, real-time solution for the analysis of excised tissue.

Confocal (right) H&E (left) images of a tissue margin from a Mohs section illustrating the entire thickness of the epidermis (EP) along with hair follicles (HF) and inflammatory cells (IC) within the dermis.