VivaScope® - The Lucid VivaScope® 1500 

AN FDA-CLEARED CONFOCAL IMAGER ASSISTS PHYSICIANS
IN CLINICAL DIAGNOSIS OF SKIN CANCER

The VivaScope^® 1500 has been the workhorse confocal imager for clinical dermatology research, resulting in well over 160 publications in peer reviewed medical journals. 

Refereed medical publications suggest the VivaScope 1500 has potential utility in many dermatologic applications. Independent clinical trial results continue to be published each month and updated publications may be found on our publications pages.

• Pigmented Lesion Assessment
  "A total score, ranging from 0 to 8, was calculated for each skin lesion... Considering lesions with a score equal to or greater than 3, a 97.3% sensitivity and a 72.3% specificity were obtained..."
  (Pellacani, et. al.)
  
  "Remarkably, using the presence or absence of monomorphic melanocytes as a single diagnostic criterion, the classification results with a sensitivity of 98.15% and a specificity of 98.89% were superior to the intuitive, integrative judgment of the observers."
  (Gerger, et. al.)
  
  
• Non-Pigmented Lesion Assessment
  "The presence of two or more criteria is 100% sensitive for the diagnosis of BCC, and with 4 or more RCM criteria present the specificity was 95.7% and sensitivity was 82.9%."
  (Nori, et. al.)
  
  
• Actinic Keratosis
  "Approximately 97.7% of all skin lesions were correctly identified as AK by RCM evaluation, whereas 2.3% were incorrectly described as normal, unaffected skin samples. Evaluation criteria consistently visualized by RCM in the presence of actinic changes included keratinoyte atypia, nuclear and cellular pleomorphism, hyperkeratosis, parakeratosis, inflammatory cells, blood vessel dilatation and solar elastosis." "
  (Ulrich, et. al.)
  
  
• Differentiating Allergic and Irritant Contact Dermatitis
  "RCM [Reflectance Confocal Microscopy] evaluation parameters included stratum corneum (SC) disruption, parakeratosis, stratum spinosum (SS) and stratum granulosum (SG) spongiosis, and exocytosis. Overall, there was high specificity for all RCM features, ranging from 95.8% to 100%. Sensitivity ranged from 51.9% to 96.3%."
  (Astner, et. al.)
  
  
• Photodamage & Aging
  "Histometric measurements by in vivo confocal laser scanning microscopy are a sensitive and non-invasive tool for characterizing and quantifying histological changes of the epidermis and papillary dermis due to ageing."
  (Sauermann, et. al.)
  
  
• Pigmentation
  "In vivo visualization of epidermal melanin was performed by reflectance-mode confocal microscopy (RCM).RCM images correlated well with the Fontana-Masson-stained sections for melanin..."
  (Yamashita, et. al.)

Contact Lucid for more information.